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Light-Mediated Transformation of Renieramycins and Semisynthesis of 4′-Pyridinecarbonyl-Substituted Renieramycin-Type Derivatives as Potential Cytotoxic Agents against Non-Small-Cell Lung Cancer Cells

The semisynthesis of renieramycin-type derivatives was achieved under mild and facile conditions by attaching a 1,3-dioxole-bridged phenolic moiety onto ring A of the renieramycin structure and adding a 4′-pyridinecarbonyl ester substituent at its C-5 or C-22 position. These were accomplished throug...

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Detalles Bibliográficos
Autores principales: Sinsook, Suwimon, Buaban, Koonchira, Iksen, Iksen, Petsri, Korrakod, Innets, Bhurichaya, Chansriniyom, Chaisak, Suwanborirux, Khanit, Yokoya, Masashi, Saito, Naoki, Pongrakhananon, Varisa, Chanvorachote, Pithi, Chamni, Supakarn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381490/
https://www.ncbi.nlm.nih.gov/pubmed/37504931
http://dx.doi.org/10.3390/md21070400