Sigma-1 Receptor Activation Is Protective against TGFβ2-Induced Extracellular Matrix Changes in Human Trabecular Meshwork Cells

The trabecular meshwork (TM) route is the principal outflow egress of the aqueous humor. Actin cytoskeletal remodeling in the TM and extracellular matrix (ECM) deposition increase TM stiffness, outflow resistance, and elevate intraocular pressure (IOP). These alterations are strongly linked to trans...

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Detalles Bibliográficos
Autores principales: Tran, Minh Ngoc, Medveczki, Timea, Besztercei, Balazs, Torok, Gyorgy, Szabo, Attila J., Gasull, Xavier, Kovacs, Illes, Fekete, Andrea, Hodrea, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381521/
https://www.ncbi.nlm.nih.gov/pubmed/37511956
http://dx.doi.org/10.3390/life13071581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381521/
https://www.ncbi.nlm.nih.gov/pubmed/37511956
http://dx.doi.org/10.3390/life13071581

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