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An Activation-Specific Anti-Mac-1 Designed-Ankyrin-Repeat-Protein Attenuates Colitis in Mice

(1) Background: Inflammatory bowel diseases are complex and multifactorial disorders of unknown etiology. The extravasation of activated leukocytes is a critical step in the pathogenesis of these diseases. Leukocyte integrin Mac-1 (α(M)β(2); CD11b/CD18) is crucial for the extravasation of myeloid ce...

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Detalles Bibliográficos
Autores principales: Bojti, Istvan, Wang, Qianqi, Bojti, Tibor, Bojti, Felicitas, Siegel, Patrick Malcolm, Heidt, Timo, Moser, Martin, Bode, Christoph, Westermann, Dirk, Peter, Karlheinz, Diehl, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381548/
https://www.ncbi.nlm.nih.gov/pubmed/37511839
http://dx.doi.org/10.3390/life13071464