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An Activation-Specific Anti-Mac-1 Designed-Ankyrin-Repeat-Protein Attenuates Colitis in Mice
(1) Background: Inflammatory bowel diseases are complex and multifactorial disorders of unknown etiology. The extravasation of activated leukocytes is a critical step in the pathogenesis of these diseases. Leukocyte integrin Mac-1 (α(M)β(2); CD11b/CD18) is crucial for the extravasation of myeloid ce...
Autores principales: | Bojti, Istvan, Wang, Qianqi, Bojti, Tibor, Bojti, Felicitas, Siegel, Patrick Malcolm, Heidt, Timo, Moser, Martin, Bode, Christoph, Westermann, Dirk, Peter, Karlheinz, Diehl, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381548/ https://www.ncbi.nlm.nih.gov/pubmed/37511839 http://dx.doi.org/10.3390/life13071464 |
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