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Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study

Background: AKT1 is a serine/threonine kinase necessary for the mediation of apoptosis, angiogenesis, metabolism, and cell proliferation in both normal and cancerous cells. The mutations in the AKT1 gene have been associated with different types of cancer. Further, the AKT1 gene mutations are also r...

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Detalles Bibliográficos
Autores principales: Zhang, Ruojun, Akhtar, Nahid, Wani, Atif Khurshid, Raza, Khalid, Kaushik, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381612/
https://www.ncbi.nlm.nih.gov/pubmed/37511907
http://dx.doi.org/10.3390/life13071532