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Dementia Is Induced via the AGEs/Iba1/iNOS Pathway in Aged KK-Ay/Tajcl Mice

The onset and exacerbation of dementia have been observed in elderly patients with type 2 diabetes. However, the underlying mechanism remains unclear. In this study, we investigated the effects of aging on the cognitive function in a mouse model of type 2 diabetes. Pathogen-free KK-Ay/TaJcl mice wer...

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Detalles Bibliográficos
Autores principales: Hiramoto, Keiichi, Imai, Masashi, Tanaka, Shota, Ooi, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381697/
https://www.ncbi.nlm.nih.gov/pubmed/37511915
http://dx.doi.org/10.3390/life13071540