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The Role of Matrix Metalloproteinases in Hemorrhagic Transformation in the Treatment of Stroke with Tissue Plasminogen Activator

Ischemic stroke is a leading cause of disability and mortality worldwide. The only approved treatment for ischemic stroke is thrombolytic therapy with tissue plasminogen activator (tPA), though this approach often leads to a severe complication: hemorrhagic transformation (HT). The pathophysiology o...

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Detalles Bibliográficos
Autores principales: Babenko, Valentina A., Fedulova, Ksenia S., Silachev, Denis N., Rahimi-Moghaddam, Parvaneh, Kalyuzhnaya, Yulia N., Demyanenko, Svetlana V., Plotnikov, Egor Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381732/
https://www.ncbi.nlm.nih.gov/pubmed/37511788
http://dx.doi.org/10.3390/jpm13071175