Conserved G-Quadruplex-Forming Sequences in Mammalian TERT Promoters and Their Effect on Mutation Frequency

SIMPLE SUMMARY: Guanine-rich genomic DNA sequences are known to be able to fold into noncanonical G-quadruplex (G4) polymorphic structures. G4s play important physiological roles in DNA replication, repair, mutagenesis, regulation of gene expression, etc. G4-forming DNA sequences (G4 motifs) predomi...

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Detalles Bibliográficos
Autores principales: Panova, Vera V., Dolinnaya, Nina G., Novoselov, Kirill A., Savitskaya, Viktoriia Yu., Chernykh, Ivan S., Kubareva, Elena A., Alexeevski, Andrei V., Zvereva, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381784/
https://www.ncbi.nlm.nih.gov/pubmed/37511853
http://dx.doi.org/10.3390/life13071478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381784/
https://www.ncbi.nlm.nih.gov/pubmed/37511853
http://dx.doi.org/10.3390/life13071478

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