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Influence of the Bile Acid Transporter Genes ABCB4, ABCB8, and ABCB11 and the Farnesoid X Receptor on the Response to Ursodeoxycholic Acid in Patients with Nonalcoholic Steatohepatitis

The prevalence of NAFLD and NASH is increasing worldwide, and there is no approved medical treatment until now. Evidence has emerged that interfering with bile acid metabolism may lead to improvement in NASH. In this study, 28 patients with elevated cholestatic liver function tests (especially GGT)...

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Detalles Bibliográficos
Autores principales: Kreimeyer, Henriette, Vogt, Katharina, Götze, Tobias, Best, Jan, Götze, Oliver, Weigt, Jochen, Kahraman, Alisan, Özçürümez, Mustafa, Kälsch, Julia, Syn, Wing-Kin, Sydor, Svenja, Canbay, Ali, Manka, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381823/
https://www.ncbi.nlm.nih.gov/pubmed/37511794
http://dx.doi.org/10.3390/jpm13071180