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Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere

The point centromere of budding yeast specifies assembly of the large kinetochore complex to mediate chromatid segregation. Kinetochores comprise the centromere-associated inner kinetochore (CCAN) complex and the microtubule-binding outer kinetochore KNL1-MIS12-NDC80 (KMN) network. The budding yeast...

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Detalles Bibliográficos
Autores principales: Dendooven, Tom, Zhang, Ziguo, Yang, Jing, McLaughlin, Stephen H., Schwab, Johannes, Scheres, Sjors H. W., Yatskevich, Stanislau, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381965/
https://www.ncbi.nlm.nih.gov/pubmed/37506202
http://dx.doi.org/10.1126/sciadv.adg7480