Brevetoxin versus Brevenal Modulation of Human Nav1 Channels

Brevetoxins (PbTx) and brevenal are marine ladder-frame polyethers. PbTx binds to and activates voltage-gated sodium (Nav) channels in native tissues, whereas brevenal antagonizes these actions. However, the effects of PbTx and brevenal on recombinant Nav channel function have not been systematicall...

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Detalles Bibliográficos
Autores principales: Finol-Urdaneta, Rocio K., Zhorov, Boris S., Baden, Daniel G., Adams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382042/
https://www.ncbi.nlm.nih.gov/pubmed/37504927
http://dx.doi.org/10.3390/md21070396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382042/
https://www.ncbi.nlm.nih.gov/pubmed/37504927
http://dx.doi.org/10.3390/md21070396

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