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CRISPR-based m(6)A modification and its potential applications in telomerase regulation

Telomerase determines cell lifespan by controlling chromosome stability and cell viability, m(6)A epigenetic modification plays an important role in the regulation of telomerase activity. Using CRISPR epigenome editing to analyze specific m(6)A modification sites in telomerase will provide an import...

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Detalles Bibliográficos
Autores principales: Yi, Mingliang, Wang, Mingyue, Xu, Yongjie, Cao, Zhikun, Ling, Yinghui, Zhang, Zijun, Cao, Hongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382234/
https://www.ncbi.nlm.nih.gov/pubmed/37519297
http://dx.doi.org/10.3389/fcell.2023.1200734