Cargando…

Bioinformatics driven discovery of small molecule compounds that modulate the FOXM1 and PPARA pathway activities in breast cancer

Our previous studies demonstrated that the FOXM1 pathway is upregulated and the PPARA pathway downregulated in breast cancer (BC), and especially in the triple negative breast cancer (TNBC) subtype. Targeting the two pathways may offer potential therapeutic strategies to treat BC, especially TNBC wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Shujun, Hu, Pingzhao, Lakowski, Ted M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382320/
https://www.ncbi.nlm.nih.gov/pubmed/36424525
http://dx.doi.org/10.1038/s41397-022-00297-1