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Imaging of large volume subcutaneous deposition using MRI: exploratory clinical study results

Subcutaneous (SC) delivery is a preferred route of administration for biotherapeutics but has predominantly been limited to volumes below 3 mL. With higher volume drug formulations emerging, understanding large volume SC (LVSC) depot localization, dispersion, and impact on the SC environment has bec...

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Detalles Bibliográficos
Autores principales: Pettis, Ronald J., Woodley, Wendy D., Ossege, Kevin C., Blum, Adam, Bolick, Natasha G., Rini, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382358/
https://www.ncbi.nlm.nih.gov/pubmed/36913105
http://dx.doi.org/10.1007/s13346-023-01318-7