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Randomized, placebo-controlled study on efficacy, safety and tolerability of drug-induced defibrinogenation for sudden sensorineural hearing loss: the lessons learned

PURPOSE: Disturbance of cochlear microcirculation is discussed as final common pathway of various inner ear diseases. Hyperfibrinogenemia causing increased plasma viscosity is a possible factor for a critical reduction of cochlear blood flow that might lead to sudden sensorineural hearing loss (SSHL...

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Detalles Bibliográficos
Autores principales: Weiss, Bernhard G., Spiegel, Jennifer L., Becker, Sven, Strieth, Sebastian, Olzowy, Bernhard, Bertlich, Mattis, Fořt, Tomáš, Mejzlik, Jan, Lenarz, Thomas, Ihler, Friedrich, Canis, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382375/
https://www.ncbi.nlm.nih.gov/pubmed/36881166
http://dx.doi.org/10.1007/s00405-023-07896-z