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Head-to-head comparison of different classes of FAP radioligands designed to increase tumor residence time: monomer, dimer, albumin binders, and small molecules vs peptides

PURPOSE: Fibroblast activation protein-α (FAP)-targeting radioligands have recently demonstrated high diagnostic potential. However, their therapeutic value is impaired by the short tumor residence time. Several strategies have been tested to overcome this limitation, but a head-to-head comparison h...

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Detalles Bibliográficos
Autores principales: Millul, Jacopo, Koepke, Lennart, Haridas, Gaonkar Raghuvir, Sparrer, Konstantin M. J., Mansi, Rosalba, Fani, Melpomeni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382406/
https://www.ncbi.nlm.nih.gov/pubmed/37261473
http://dx.doi.org/10.1007/s00259-023-06272-7