Response surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity potential

Vanillic acid (VA) is a phenolic compound with potential antioxidant activity, which improves ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers poor bioavailability owing to its poor solubility. VA-loaded pharmacosomes were optimized using a central composit...

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Detalles Bibliográficos
Autores principales: Dawoud, Marwa H. S., Zaafan, Mai A., Saleh, Sarah S., Mannaa, Islam M., Sweed, Nabila M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382421/
https://www.ncbi.nlm.nih.gov/pubmed/37017879
http://dx.doi.org/10.1007/s13346-023-01315-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382421/
https://www.ncbi.nlm.nih.gov/pubmed/37017879
http://dx.doi.org/10.1007/s13346-023-01315-w

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