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N-Acetyltransferase 9 ameliorates Aβ42-mediated neurodegeneration in the Drosophila eye

Alzheimer’s disease (AD), a progressive neurodegenerative disorder, manifests as accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of neurofibrillary tangles (NFTs) that results in microtubule destabilization. Targeted expression of human Aβ42 (GMR > Aβ42) in developin...

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Detalles Bibliográficos
Autores principales: Deshpande, Prajakta, Chimata, Anuradha Venkatakrishnan, Snider, Emily, Singh, Aditi, Kango-Singh, Madhuri, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382493/
https://www.ncbi.nlm.nih.gov/pubmed/37507384
http://dx.doi.org/10.1038/s41419-023-05973-z