NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes

Injury or stress can induce intracellular translocation and release of nuclear HMGB1, a DAMP molecule known to participate in inflammation and other pathological processes. Active release of HMGB1 from stimulated macrophages can be mediated by inflammasomes, which cleave Gasdermin D to form pores on...

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Detalles Bibliográficos
Autores principales: Khambu, Bilon, Cai, Genxiang, Liu, Gang, Bailey, Niani Tiaye, Mercer, Arissa A., Baral, Kamal, Ma, Michelle, Chen, Xiaoyun, Li, Yu, Yin, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382497/
https://www.ncbi.nlm.nih.gov/pubmed/37507374
http://dx.doi.org/10.1038/s41420-023-01495-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382497/
https://www.ncbi.nlm.nih.gov/pubmed/37507374
http://dx.doi.org/10.1038/s41420-023-01495-x

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