Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex

Opioid use disorder (OUD) is influenced by genetic and environmental factors. While recent research suggests epigenetic disturbances in OUD, this is mostly limited to DNA methylation (5mC). DNA hydroxymethylation (5hmC) has been widely understudied. We conducted a multi-omics profiling of OUD in a m...

Descripción completa

Detalles Bibliográficos
Autores principales: Rompala, Gregory, Nagamatsu, Sheila T., Martínez-Magaña, José Jaime, Nuñez-Ríos, Diana L., Wang, Jiawei, Girgenti, Matthew J., Krystal, John H., Gelernter, Joel, Hurd, Yasmin L., Montalvo-Ortiz, Janitza L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382503/
https://www.ncbi.nlm.nih.gov/pubmed/37507366
http://dx.doi.org/10.1038/s41467-023-40285-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382503/
https://www.ncbi.nlm.nih.gov/pubmed/37507366
http://dx.doi.org/10.1038/s41467-023-40285-y

Ejemplares similares