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UCHL1 facilitates protein aggregates clearance to enhance neural stem cell activation in spinal cord injury

Activation of endogenous neural stem cells (NSCs) is greatly significant for the adult neurogenesis; however, it is extremely limited in the spinal cord after injury. Recent evidence suggests that accumulation of protein aggregates impairs the ability of quiescent NSCs to activate. Ubiquitin c-termi...

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Detalles Bibliográficos
Autores principales: Ding, Lu, Chu, Weiwei, Xia, Yu, Shi, Ming, Li, Tian, Zhou, Feng-Quan, Deng, David Y. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382505/
https://www.ncbi.nlm.nih.gov/pubmed/37507386
http://dx.doi.org/10.1038/s41419-023-06003-8