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Rejuvenating effects of young extracellular vesicles in aged rats and in cellular models of human senescence
Rejuvenation of an old organism was achieved in heterochronic parabiosis experiments, implicating different soluble factors in this effect. Extracellular vesicles (EVs) are the secretory effectors of many cells, including cardiosphere-derived cells (CDCs) with demonstrated anti-senescent effect. 1....
Autores principales: | Grigorian Shamagian, Lilian, Rogers, Russell G., Luther, Kristin, Angert, David, Echavez, Antonio, Liu, Weixin, Middleton, Ryan, Antes, Travis, Valle, Jackelyn, Fourier, Mario, Sanchez, Liz, Jaghatspanyan, Eva, Mariscal, Javier, Zhang, Rui, Marbán, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382547/ https://www.ncbi.nlm.nih.gov/pubmed/37507448 http://dx.doi.org/10.1038/s41598-023-39370-5 |
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