Rejuvenating effects of young extracellular vesicles in aged rats and in cellular models of human senescence

Rejuvenation of an old organism was achieved in heterochronic parabiosis experiments, implicating different soluble factors in this effect. Extracellular vesicles (EVs) are the secretory effectors of many cells, including cardiosphere-derived cells (CDCs) with demonstrated anti-senescent effect. 1....

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Detalles Bibliográficos
Autores principales: Grigorian Shamagian, Lilian, Rogers, Russell G., Luther, Kristin, Angert, David, Echavez, Antonio, Liu, Weixin, Middleton, Ryan, Antes, Travis, Valle, Jackelyn, Fourier, Mario, Sanchez, Liz, Jaghatspanyan, Eva, Mariscal, Javier, Zhang, Rui, Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382547/
https://www.ncbi.nlm.nih.gov/pubmed/37507448
http://dx.doi.org/10.1038/s41598-023-39370-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382547/
https://www.ncbi.nlm.nih.gov/pubmed/37507448
http://dx.doi.org/10.1038/s41598-023-39370-5

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