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Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

Cardiosphere‐derived cells (CDCs) reduce myocardial infarct size via secreted extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage polarization. We questioned whether short non‐coding RNA species of unknown function within CDC‐EVs contribute to cardioprotection. The most abun...

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Detalles Bibliográficos
Autores principales: Cambier, Linda, de Couto, Geoffrey, Ibrahim, Ahmed, Echavez, Antonio K, Valle, Jackelyn, Liu, Weixin, Kreke, Michelle, Smith, Rachel R, Marbán, Linda, Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331234/
https://www.ncbi.nlm.nih.gov/pubmed/28167565
http://dx.doi.org/10.15252/emmm.201606924