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Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

BACKGROUND: Extracellular vesicles (EVs) and exosomes are nano-sized, membrane-bound vesicles shed by most eukaryotic cells studied to date. EVs play key signaling roles in cellular development, cancer metastasis, immune modulation and tissue regeneration. Attempts to modify exosomes to increase the...

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Detalles Bibliográficos
Autores principales: Antes, Travis J., Middleton, Ryan C., Luther, Kristin M., Ijichi, Takeshi, Peck, Kiel A., Liu, Weixin Jane, Valle, Jackie, Echavez, Antonio K., Marbán, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116387/
https://www.ncbi.nlm.nih.gov/pubmed/30165851
http://dx.doi.org/10.1186/s12951-018-0388-4