Adjuvant effects of combination monophosphoryl lipid A and poly I:C on antigen-specific immune responses and protective efficacy of influenza vaccines

Toll-like receptor (TLR) agonists improve vaccine immunogenicity and efficacy, but they are currently unlicensed as adjuvants in influenza vaccines. This study aimed to investigate whether a combination of monophosphoryl lipid A (MPL, a TLR4 agonist) and polyriboinosinic polyribocytidylic acid (poly...

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Detalles Bibliográficos
Autores principales: Le, Chau Thuy Tien, Ahn, So Yeon, Ho, Thi Len, Lee, Jueun, Lee, Dong-Ha, Hwang, Hye Suk, Kang, Sang-Moo, Ko, Eun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382554/
https://www.ncbi.nlm.nih.gov/pubmed/37507413
http://dx.doi.org/10.1038/s41598-023-39210-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382554/
https://www.ncbi.nlm.nih.gov/pubmed/37507413
http://dx.doi.org/10.1038/s41598-023-39210-6

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