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Differential exon usage of developmental genes is associated with deregulated epigenetic marks

Alternative exon usage is known to affect a large portion of genes in mammalian genomes. Importantly, different splice isoforms sometimes possess distinctly different protein functions. Here, we analyzed data from the Human Epigenome Atlas for 11 different human adult tissues and for 8 cultured cell...

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Detalles Bibliográficos
Autores principales: Do, Hoang Thu Trang, Shanak, Siba, Barghash, Ahmad, Helms, Volkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382575/
https://www.ncbi.nlm.nih.gov/pubmed/37507411
http://dx.doi.org/10.1038/s41598-023-38879-z