NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons

We describe a patient haploinsufficient for the neuronal RNA binding protein NOVA1 who developed a behavioral motor hyperactivity disorder, suggesting a role of NOVA1 in postnatal motor inhibition. To investigate Nova1’s action in adult Gad2(+) inhibitory neurons, we generated a conditional Nova1-nu...

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Detalles Bibliográficos
Autores principales: Tajima, Yoko, Ito, Keiichi, Yuan, Yuan, Frank, Mayu O., Saito, Yuhki, Darnell, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382602/
https://www.ncbi.nlm.nih.gov/pubmed/36716149
http://dx.doi.org/10.1016/j.celrep.2023.112050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382602/
https://www.ncbi.nlm.nih.gov/pubmed/36716149
http://dx.doi.org/10.1016/j.celrep.2023.112050

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