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NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons
We describe a patient haploinsufficient for the neuronal RNA binding protein NOVA1 who developed a behavioral motor hyperactivity disorder, suggesting a role of NOVA1 in postnatal motor inhibition. To investigate Nova1’s action in adult Gad2(+) inhibitory neurons, we generated a conditional Nova1-nu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382602/ https://www.ncbi.nlm.nih.gov/pubmed/36716149 http://dx.doi.org/10.1016/j.celrep.2023.112050 |