GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion

Exercise is a first-line treatment for type 2 diabetes and preserves β-cell function by hitherto unknown mechanisms. We postulated that proteins from contracting skeletal muscle may act as cellular signals to regulate pancreatic β-cell function. We used electric pulse stimulation (EPS) to induce con...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hui, Mulya, Anny, Nieuwoudt, Stephan, Vandanmagsar, Bolormaa, McDowell, Ruth, Heintz, Elizabeth C., Zunica, Elizabeth R.M., Collier, J. Jason, Bozadjieva-Kramer, Nadejda, Seeley, Randy J., Axelrod, Christopher L., Kirwan, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382648/
https://www.ncbi.nlm.nih.gov/pubmed/37224335
http://dx.doi.org/10.2337/db22-0019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382648/
https://www.ncbi.nlm.nih.gov/pubmed/37224335
http://dx.doi.org/10.2337/db22-0019

Ejemplares similares