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GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion

Exercise is a first-line treatment for type 2 diabetes and preserves β-cell function by hitherto unknown mechanisms. We postulated that proteins from contracting skeletal muscle may act as cellular signals to regulate pancreatic β-cell function. We used electric pulse stimulation (EPS) to induce con...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Mulya, Anny, Nieuwoudt, Stephan, Vandanmagsar, Bolormaa, McDowell, Ruth, Heintz, Elizabeth C., Zunica, Elizabeth R.M., Collier, J. Jason, Bozadjieva-Kramer, Nadejda, Seeley, Randy J., Axelrod, Christopher L., Kirwan, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2023
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382648/ https://www.ncbi.nlm.nih.gov/pubmed/37224335 http://dx.doi.org/10.2337/db22-0019

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