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The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase–LRP4 receptor complex by agrin at the neuromuscular junction

Collagen Q (ColQ) is a nonfibrillar collagen that plays a crucial role at the vertebrate neuromuscular junction (NMJ) by anchoring acetylcholinesterase to the synapse. ColQ also functions in signaling, as it regulates acetylcholine receptor clustering and synaptic gene expression, in a manner depend...

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Detalles Bibliográficos
Autores principales: Uyen Dao, Thi Minh, Barbeau, Susie, Messéant, Julien, Della-Gaspera, Bruno, Bouceba, Tahar, Semprez, Fannie, Legay, Claire, Dobbertin, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382678/
https://www.ncbi.nlm.nih.gov/pubmed/37356721
http://dx.doi.org/10.1016/j.jbc.2023.104962