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The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase–LRP4 receptor complex by agrin at the neuromuscular junction
Collagen Q (ColQ) is a nonfibrillar collagen that plays a crucial role at the vertebrate neuromuscular junction (NMJ) by anchoring acetylcholinesterase to the synapse. ColQ also functions in signaling, as it regulates acetylcholine receptor clustering and synaptic gene expression, in a manner depend...
Autores principales: | Uyen Dao, Thi Minh, Barbeau, Susie, Messéant, Julien, Della-Gaspera, Bruno, Bouceba, Tahar, Semprez, Fannie, Legay, Claire, Dobbertin, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382678/ https://www.ncbi.nlm.nih.gov/pubmed/37356721 http://dx.doi.org/10.1016/j.jbc.2023.104962 |
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