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Specificity of Psychiatric Polygenic Risk Scores and Their Effects on Associated Risk Phenotypes

BACKGROUND: Polygenic risk scores (PRSs) are indices of genetic liability for illness, but their clinical utility for predicting risk for a specific psychiatric disorder is limited. Genetic overlap among disorders and their effects on allied phenotypes may be a possible explanation, but this has bee...

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Detalles Bibliográficos
Autores principales: Rodrigue, Amanda L., Mathias, Samuel R., Knowles, Emma E.M., Mollon, Josephine, Almasy, Laura, Schultz, Laura, Turner, Jessica, Calhoun, Vince, Glahn, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382704/
https://www.ncbi.nlm.nih.gov/pubmed/37519455
http://dx.doi.org/10.1016/j.bpsgos.2022.05.008