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Specificity of Psychiatric Polygenic Risk Scores and Their Effects on Associated Risk Phenotypes
BACKGROUND: Polygenic risk scores (PRSs) are indices of genetic liability for illness, but their clinical utility for predicting risk for a specific psychiatric disorder is limited. Genetic overlap among disorders and their effects on allied phenotypes may be a possible explanation, but this has bee...
Autores principales: | Rodrigue, Amanda L., Mathias, Samuel R., Knowles, Emma E.M., Mollon, Josephine, Almasy, Laura, Schultz, Laura, Turner, Jessica, Calhoun, Vince, Glahn, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382704/ https://www.ncbi.nlm.nih.gov/pubmed/37519455 http://dx.doi.org/10.1016/j.bpsgos.2022.05.008 |
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