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Proteomic Analysis Identifies Circulating Proteins Associated With Plasma Amyloid-β and Incident Dementia

BACKGROUND: Plasma amyloid-β (Aβ) (Aβ(42), Aβ(40), and Aβ(42)/Aβ(40)), biomarkers of the Alzheimer’s form of dementia, are under consideration for clinical use. The associations of these peptides with circulating proteins may identify novel plasma biomarkers of dementia and inform peripheral factors...

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Detalles Bibliográficos
Autores principales: Tin, Adrienne, Sullivan, Kevin J., Walker, Keenan A., Bressler, Jan, Talluri, Rajesh, Yu, Bing, Simino, Jeanette, Gudmundsdottir, Valborg, Emilsson, Valur, Jennings, Lori L., Launer, Lenore, Mei, Hao, Boerwinkle, Eric, Windham, B. Gwen, Gottesman, Rebecca, Gudnason, Vilmundur, Coresh, Josef, Fornage, Myriam, Mosley, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382706/
https://www.ncbi.nlm.nih.gov/pubmed/37519456
http://dx.doi.org/10.1016/j.bpsgos.2022.04.005