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GWAS-identified telomere length associated genetic variants predict risk of recurrence of HPV-positive oropharyngeal cancer after definitive radiotherapy

BACKGROUND: Lymphocyte telomere length (LTL)-related genetic variants may modulate LTL and affect recurrence of squamous cell carcinoma of the oropharynx (SCCOP). METHODS: A total of 1013 patients with incident SCCOP were recruited and genotyped for 16 genome-wide association study (GWAS)-identified...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Wei, Peng, Liu, Hongliang, Wu, Jia, Gross, Neil D., Sikora, Andrew G., Wei, Qingyi, Shete, Sanjay, Zafereo, Mark E., Liu, Jisheng, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382868/
https://www.ncbi.nlm.nih.gov/pubmed/37487414
http://dx.doi.org/10.1016/j.ebiom.2023.104722