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SIRT1/Nrf2/NF-κB Signaling Mediates Anti-Inflammatory and Anti-Apoptotic Activities of Oleanolic Acid in a Mouse Model of Acute Hepatorenal Damage

Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti-atherosclerotic, hypolipidemic, and gastroprotective. However, its effects on hepatorenal damage remain unclear. The prote...

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Detalles Bibliográficos
Autores principales: Alqrad, Manea A. I., El-Agamy, Dina S., Ibrahim, Sabrin R. M., Sirwi, Alaa, Abdallah, Hossam M., Abdel-Sattar, Essam, El-Halawany, Ali M., Elsaed, Wael M., Mohamed, Gamal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383078/
https://www.ncbi.nlm.nih.gov/pubmed/37512162
http://dx.doi.org/10.3390/medicina59071351