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SIRT1/Nrf2/NF-κB Signaling Mediates Anti-Inflammatory and Anti-Apoptotic Activities of Oleanolic Acid in a Mouse Model of Acute Hepatorenal Damage
Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti-atherosclerotic, hypolipidemic, and gastroprotective. However, its effects on hepatorenal damage remain unclear. The prote...
Autores principales: | Alqrad, Manea A. I., El-Agamy, Dina S., Ibrahim, Sabrin R. M., Sirwi, Alaa, Abdallah, Hossam M., Abdel-Sattar, Essam, El-Halawany, Ali M., Elsaed, Wael M., Mohamed, Gamal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383078/ https://www.ncbi.nlm.nih.gov/pubmed/37512162 http://dx.doi.org/10.3390/medicina59071351 |
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