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Tumor Necrosis Factor and Interleukin-1β Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), utilizes the host receptor angiotensin-converting enzyme 2 (ACE2) and the auxiliary receptor Neuropilin-1 (NRP1) to enter host cells. NRP1 has another isoform, NRP2, whose function in COVI...

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Detalles Bibliográficos
Autores principales: Ishitoku, Michinori, Mokuda, Sho, Araki, Kei, Watanabe, Hirofumi, Kohno, Hiroki, Sugimoto, Tomohiro, Yoshida, Yusuke, Sakaguchi, Takemasa, Masumoto, Junya, Hirata, Shintaro, Sugiyama, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383177/
https://www.ncbi.nlm.nih.gov/pubmed/37515185
http://dx.doi.org/10.3390/v15071498