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Assessing the Influence of Propylthiouracil and Phenytoin on the Metabolomes of the Thyroid, Liver, and Plasma in Rats

The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport. The therapeutic drugs propylthiouracil (PTU) and phenytoin are known to induce hypothyroidism and decrease blood thyroid hormone levels. To analyze th...

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Detalles Bibliográficos
Autores principales: Wang, Zhipeng, Haange, Sven-Bastiaan, Haake, Volker, Huisinga, Maike, Kamp, Hennicke, Buesen, Roland, Schubert, Kristin, Canzler, Sebastian, Hackermüller, Jörg, Rolle-Kampczyk, Ulrike, von Bergen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383188/
https://www.ncbi.nlm.nih.gov/pubmed/37512556
http://dx.doi.org/10.3390/metabo13070847