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Assessing the Influence of Propylthiouracil and Phenytoin on the Metabolomes of the Thyroid, Liver, and Plasma in Rats
The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport. The therapeutic drugs propylthiouracil (PTU) and phenytoin are known to induce hypothyroidism and decrease blood thyroid hormone levels. To analyze th...
Autores principales: | Wang, Zhipeng, Haange, Sven-Bastiaan, Haake, Volker, Huisinga, Maike, Kamp, Hennicke, Buesen, Roland, Schubert, Kristin, Canzler, Sebastian, Hackermüller, Jörg, Rolle-Kampczyk, Ulrike, von Bergen, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383188/ https://www.ncbi.nlm.nih.gov/pubmed/37512556 http://dx.doi.org/10.3390/metabo13070847 |
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