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Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of cancer-related deaths globally. Evidence shows that over 90% of CRC cases are initiated by a deregulated Wingless Integrated Type-1 (WNT)/β-catenin signaling pathway. The WNT/β-catenin pathway also promotes CRC...

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Detalles Bibliográficos
Autores principales: Quarshie, Jude Tetteh, Fosu, Kwadwo, Offei, Nicholas Awuku, Sobo, Augustine Kojo, Quaye, Osbourne, Aikins, Anastasia Rosebud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383422/
https://www.ncbi.nlm.nih.gov/pubmed/37513937
http://dx.doi.org/10.3390/ph16071026