Polylysine-Containing Hydrogel Formulation of Fuzapladib, Inhibitor of Leukocyte-Function Associated Antigen-1 (LFA-1) Activation, for Sustained Release

The aim of the present study was to develop an injectable hydrogel (HG) formulation of fuzapladib sodium (FZP), an animal drug for acute pancreatitis (AP), with the use of polyethyleneoxide (PEO) and polylysine (pLys), a cationic polymer. A mixture of pLys and FZP was added to PEO to prepare an HG f...

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Detalles Bibliográficos
Autores principales: Higuchi, Koji, Yamada, Kohei, Kihara, Tsubasa, Makino, Keisuke, Sasaki, Kenta, Shindo, Takeshi, Shikama, Hiroshi, Sato, Hideyuki, Onoue, Satomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383447/
https://www.ncbi.nlm.nih.gov/pubmed/37513199
http://dx.doi.org/10.3390/molecules28145325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383447/
https://www.ncbi.nlm.nih.gov/pubmed/37513199
http://dx.doi.org/10.3390/molecules28145325

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