Finding a Novel Chalcone–Cinnamic Acid Chimeric Compound with Antiproliferative Activity against MCF-7 Cell Line Using a Free-Wilson Type Approach

In this work, we carried out the design and synthesis of new chimeric compounds from the natural cytotoxic chalcone 2′,4′-dihydroxychalcone (2′,4′-DHC, A) in combination with cinnamic acids. For this purpose, a descriptive and predictive quantitative structure–activity relationship (QSAR) model was...

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Detalles Bibliográficos
Autores principales: Ventura-Salazar, Isis A. Y., Palacios-Can, Francisco J., González-Maya, Leticia, Sánchez-Carranza, Jessica Nayelli, Antunez-Mojica, Mayra, Razo-Hernández, Rodrigo Said, Alvarez, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383513/
https://www.ncbi.nlm.nih.gov/pubmed/37513358
http://dx.doi.org/10.3390/molecules28145486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383513/
https://www.ncbi.nlm.nih.gov/pubmed/37513358
http://dx.doi.org/10.3390/molecules28145486

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