Cargando…

Finding a Novel Chalcone–Cinnamic Acid Chimeric Compound with Antiproliferative Activity against MCF-7 Cell Line Using a Free-Wilson Type Approach

In this work, we carried out the design and synthesis of new chimeric compounds from the natural cytotoxic chalcone 2′,4′-dihydroxychalcone (2′,4′-DHC, A) in combination with cinnamic acids. For this purpose, a descriptive and predictive quantitative structure–activity relationship (QSAR) model was...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ventura-Salazar, Isis A. Y., Palacios-Can, Francisco J., González-Maya, Leticia, Sánchez-Carranza, Jessica Nayelli, Antunez-Mojica, Mayra, Razo-Hernández, Rodrigo Said, Alvarez, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383513/ https://www.ncbi.nlm.nih.gov/pubmed/37513358 http://dx.doi.org/10.3390/molecules28145486

Ejemplares similares

Molecular Mechanisms of Antiproliferative Effects of Natural Chalcones
por: Michalkova, Radka, et al.
Publicado: (2021)

Methoxylated Cinnamic Esters with Antiproliferative and Antimetastatic Effects on Human Lung Adenocarcinoma Cells
por: Sampaio, João Graciano, et al.
Publicado: (2023)

Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress
por: Takac, Peter, et al.
Publicado: (2020)

Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents
por: Lu, Chao-Fan, et al.
Publicado: (2020)

Synthesis and Antiproliferative Activity of Novel Dehydroabietic Acid-Chalcone Hybrids
por: Grigoropoulou, Sophia, et al.
Publicado: (2022)

Synthesis and biological evaluation of phosphatidylcholines with cinnamic and 3-methoxycinnamic acids with potent antiproliferative activity
por: Czarnecka, Marta, et al.
Publicado: (2018)

Mechanisms underlying the antiproliferative effects of a series of quinoxaline-derived chalcones
por: Mielcke, Tânia R., et al.
Publicado: (2017)

The isolation and expression analysis of cinnamate 4-hydroxylase and chalcone synthase genes of Scrophularia striata under different abiotic elicitors
por: Rostami, Zeinab, et al.
Publicado: (2022)

Design, Synthesis, and Evaluation of Novel Indole Hybrid Chalcones and Their Antiproliferative and Antioxidant Activity
por: Kudličková, Zuzana, et al.
Publicado: (2023)

The antiproliferative potential and mechanism of action of metformin in MCF-7 cells
por: Bekezhankyzy, Zhibek, et al.
Publicado: (2023)

Creatininium cinnamate
por: Ali, A. Jahubar, et al.
Publicado: (2011)

Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells
por: dos Santos, Mariana Bastos, et al.
Publicado: (2019)

Chalcone Methoxy Derivatives Exhibit Antiproliferative and Proapoptotic Activity on Canine Lymphoma and Leukemia Cells
por: Pawlak, Aleksandra, et al.
Publicado: (2020)

A New Chalcone Derivative with Promising Antiproliferative and Anti-Invasion Activities in Glioblastoma Cells
por: Mendanha, Daniel, et al.
Publicado: (2021)

Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells
por: Rodríguez, Irene, et al.
Publicado: (2021)

Antiproliferative effect of dexamethasone in the MCF-7 breast cancer cell line
por: BUXANT, FREDERIC, et al.
Publicado: (2015)

Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells
por: Estévez-Sarmiento, Francisco, et al.
Publicado: (2022)

Achillin Increases Chemosensitivity to Paclitaxel, Overcoming Resistance and Enhancing Apoptosis in Human Hepatocellular Carcinoma Cell Line Resistant to Paclitaxel (Hep3B/PTX)
por: Sanchez-Carranza, Jessica Nayelli, et al.
Publicado: (2019)

ANTIPROLIFERATIVE EFFECT ON BREAST CANCER (MCF7) OF MORINGA OLEIFERA SEED EXTRACTS
por: Adebayo, Ismail Abiola, et al.
Publicado: (2017)

Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities
por: Shaik, Afzal B., et al.
Publicado: (2020)

Lignans from Bursera fagaroides Affect In Vivo Cell Behavior by Disturbing the Tubulin Cytoskeleton in Zebrafish Embryos
por: Antúnez-Mojica, Mayra, et al.
Publicado: (2018)

Cinnamate-based DNA photolithography
por: Feng, Lang, et al.
Publicado: (2013)

Multifunctional Cinnamic Acid Derivatives
por: Peperidou, Aikaterini, et al.
Publicado: (2017)

Heteroleptic Copper(II) Complexes Containing 2′-Hydroxy-4-(Dimethylamino)Chalcone Show Strong Antiproliferative Activity
por: Trávníček, Zdeněk, et al.
Publicado: (2023)

Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast Cancer
por: Zhang, Jun-Xia, et al.
Publicado: (2018)

Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7
por: Buranrat, Benjaporn, et al.
Publicado: (2019)

Mechanisms for Improving Hepatic Glucolipid Metabolism by Cinnamic Acid and Cinnamic Aldehyde: An Insight Provided by Multi-Omics
por: Wu, You, et al.
Publicado: (2022)

Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells
por: Liu, Ming, et al.
Publicado: (2016)

Exploring the Therapeutic Potential of trans-Chalcone: Modulation of MicroRNAs Linked to Breast Cancer Progression in MCF-7 Cells
por: Komoto, Tatiana Takahasi, et al.
Publicado: (2023)

Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents
por: Zhang, Sai-Yang, et al.
Publicado: (2016)

Synergism Potentiates Oxidative Antiproliferative Effects of Naringenin and Quercetin in MCF-7 Breast Cancer Cells
por: Rhman, Mahasin Abdel, et al.
Publicado: (2022)

The Effect of Different Glucose Concentrations on the Antiproliferative Activity of Metformin in MCF-7 Breast Cancer Cells
por: Nurzhan, Sholpan, et al.
Publicado: (2023)

Multitarget Molecular Hybrids of Cinnamic Acids
por: Peperidou, Aikaterini, et al.
Publicado: (2014)

Cinnamic Acid Derivatives and Their Biological Efficacy
por: Ruwizhi, Ngonidzashe, et al.
Publicado: (2020)

Cinnamic Derivatives as Antitubercular Agents: Characterization by Quantitative Structure–Activity Relationship Studies
por: Teixeira, Cátia, et al.
Publicado: (2020)

Cis-trimethoxystilbene, exhibits higher genotoxic and antiproliferative effects than its isomer trans-trimethoxystilbene in MCF-7 and MCF-10A cell lines
por: Gonçalves, Natália dos Santos, et al.
Publicado: (2021)

Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines
por: Safwat, Ghada M., et al.
Publicado: (2021)

PAMAM-G4 protect the N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) and maintain its antiproliferative effects on MCF-7
por: Ortiz-Morales, Alma Alicia, et al.
Publicado: (2023)

Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation
por: Kasetti, Ashok Babu, et al.
Publicado: (2021)

Enhanced and Selective Antiproliferative Activity of Methotrexate-Functionalized-Nanocapsules to Human Breast Cancer Cells (MCF-7)
por: de Oliveira, Catiúscia P., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dk6ma7u1lrfr58j8uu7ld8b10m