Exploring the Molecular Targets for the Antidepressant and Antisuicidal Effects of Ketamine Enantiomers by Using Network Pharmacology and Molecular Docking

Ketamine, a racemic mixture of esketamine (S-ketamine) and arketamine (R-ketamine), has received particular attention for its rapid antidepressant and antisuicidal effects. NMDA receptor inhibition has been indicated as one of the main mechanisms of action of the racemic mixture, but other pharmacol...

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Detalles Bibliográficos
Autores principales: Altê, Glorister A., Rodrigues, Ana Lúcia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383558/
https://www.ncbi.nlm.nih.gov/pubmed/37513925
http://dx.doi.org/10.3390/ph16071013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383558/
https://www.ncbi.nlm.nih.gov/pubmed/37513925
http://dx.doi.org/10.3390/ph16071013

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