Bioanalytical LC-QTOF/MS Method for a N-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies

The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests. In order to evaluate its pharmacokinetic properties, a liquid chromatography method coupled...

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Detalles Bibliográficos
Autores principales: Ramos, Ana Cláudia M., Rezende, Kênnia R., Teixeira, Carolina M., Fernandes, Aline R., Santos, Heloa, Machado, Rúbia Darc, Menegatti, Ricardo, Vaz, Boniek G., Chaves, Andréa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383682/
https://www.ncbi.nlm.nih.gov/pubmed/37513842
http://dx.doi.org/10.3390/ph16070930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383682/
https://www.ncbi.nlm.nih.gov/pubmed/37513842
http://dx.doi.org/10.3390/ph16070930

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