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Silver-Catalyzed Decarboxylative Acylation of Isocyanides Accesses to α-Ketoamides with Air as a Sole Oxidant

α-Ketoamide moieties, as privileged units, may represent a valuable option to develop compounds with favorable biological activities, such as low toxicity, promising PK and drug-like properties. An efficient silver-catalyzed decarboxylative acylation of α-oxocarboxylic acids with isocyanides was dev...

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Detalles Bibliográficos
Autores principales: Xu, Jia, Li, Xue, Chen, Xing-Yu, He, Yu-Ting, Lei, Jie, Chen, Zhong-Zhu, Xu, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383724/
https://www.ncbi.nlm.nih.gov/pubmed/37513215
http://dx.doi.org/10.3390/molecules28145342