Cargando…

Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms

This study investigated the effect of nicotinamide (NAM) supplementation on the development of brain inflammation and microglial activation in a mouse model of type 1 diabetes mellitus. C57BL/6J male mice, which were made diabetic with five consecutive, low-dose (55 mg/kg i.p.) streptozotocin (STZ)...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres-Méndez, Jeimy Katherine, Niño-Narvión, Julia, Martinez-Santos, Patricia, Diarte-Añazco, Elena María Goretti, Méndez-Lara, Karen Alejandra, del Olmo, Tania Vázquez, Rotllan, Noemi, Julián, Maria Teresa, Alonso, Núria, Mauricio, Didac, Camacho, Mercedes, Muñoz, Juan Pablo, Rossell, Joana, Julve, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383777/
https://www.ncbi.nlm.nih.gov/pubmed/37513501
http://dx.doi.org/10.3390/nu15143083